Arginine

Question: Is it advisable to drink both, whey protein isolated and an arginine supplement before going to sleep? I want to know if it's ok to drink the arginine supplement and 30 minutes later drink one milkshake of whey protein isolated before going to sleep. Do they compete with each other or this mix is beneficial? thank you.

Answer: Actually Whey protein is not the best before bed. You need Casein protein. In powder or you can eat Cottage cheese. Take the Arginine before working out and 45mns before bed time.

Question: How much L-Arginine would I have to take to experience an increase in GH production.? I am a 5'9 male, 19 years old. I have had a bone scan and my growth plates haven't yet ossified meaning I can still experience an increase in height. If I wanted to ameliorate said increase, precisely what dosage of amino acids like L-Arginine would I have to take in order to experience one inch of growth over the next few years. I already engage in hours of strenuous physical exercise every day.

Answer: Wouldn't it be wise to ask your Dr this question in stead to some strangers you don't know? He can tell you what to take and not give you a wild guess Colors

Question: Can L-Arginine increase your risk of heart attack even if you have not already had a heart attack? I've read that if you have had a heart attack, taking L-Arginine supplements will increase your chances of having and dying from another heart attack. But what about people who have not yet had a heart attack, but have the precursors of a heart attack, such as high cholesterol, hardening of the arteries, high blood pressure, etc.? Does supplementing with L-Arginine increase their risk also? To answer Scottsdalehigh64's question, I've read on several websites that L-Arginine supplementation helps with circulation problems, which I think I have. Also, as you mentioned, I do eat well, exercise, etc.

Answer: Below you will find links to a couple of scientific papers on this subject. There is a large body of scientific evidence that L-Arginine supplementation has potentially positive benefits in patients with cardiovascular disease. L-Arginine is the precursor for the synthesis of Nitric Oxide by the three enzymes called Nitric Oxide Synthase (NOS). Endothelial NOS (eNOS) is the form of the enzyme that produces Nitric Oxide in the lining of the arteries (the endothelium) where it is VITAL for vascular health and prevention of cardiovascular diseases. As the attached links indicate, the level of ADMA - Asymmetric Dimethylarginine in the patient may determine whether or not L-Arginine supplements are beneficial. The one scientific paper that reported a possible increased risk of heart attack in patients supplemented with L-Arginine was a terribly done and poorly reported (dishonest) study that has been completely "debunked" (1) by one of the world's leading researchers in this field - Louis Ignarro, M.D. (recipient of the Nobel Prize in 1998 for his research on Nitric Oxide). One BAD study does not make "truth". http://jn.nutrition.org/cgi/content/full/137/6/1650S http://circ.ahajournals.org/cgi/content/full/113/13/1708 It is also important to understand that the cofactor for NOS is tetrahydrobiopterin (BH4), and levels of this cofactor can impact the ability of the enzyme to convert L-Arginine to Nitric Oxide. Numerous studies indicate that maintaining the high levels of BH4 needed in the body to make Nitric Oxide requires adequate amounts of Vitamin C and Folate - and, supplementation of these micronutrients can significantly affect endothelial health and Nitric Oxide production. http://www.ncbi.nlm.nih.gov/pubmed/16344367?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_Discovery_RA&linkpos=2&log$=relatedarticles&logdbfrom=pubmed Best wishes and good luck. p.s. one additional point: vegetable proteins (e.g. soy) are high in Arginine content (meat proteins are much lower). Thus, Vegetarians "naturally" have a higher intake of L-Arginine than meat eaters. It is interesting that Vegetarians have a much lower risk of cardiovascular disease than meat eaters, and some researchers have hypothesized that this difference in amino acid content of the diets may be a factor.

Question: What is a healthy ratio of lysine to arginine? lysine and arginine are both essential amino acids. I don't think humans can synthesise these amino acids and I have heard that we should take in more lysine than arginine. Is that true?

Answer: Actually, arginine is not one of the ten "essential" amino acids identified by the World Health Organization. All humans synthesize arginine, but infants do not synthesize enough, so they need to get extra through food. Because arginine needs depend on how much the body is synthesizing, it's not possible to say that you need to consume it in a certain ratio to other amino acids, as you can with the true "essential" acids. If you are doing research for your own diet, I would not worry about arginine (or any animo acids unless you have reason to suspect a deficiency). If you are raising a vegetarian child, I again would not worry because your child is probably getting enough arginine from dairy products. If you are raising a vegan child, I would consult your child's physician, but note that these vegan foods contain arginine: Chocolate, wheat germ and flour, buckwheat, granola, oatmeal, nuts (coconut, pecans, cashews, walnuts, almonds, Brazil nuts, hazel nuts, peanuts), seeds (pumpkin, sesame, sunflower), chick peas, and cooked soybeans. _ Lysine as a Limiting Amino Acid _ While dairy is a good source of arginine, it is not such a good source of lysine. Lysine is one of the true "essential" animo acids because your body can't synthesize it. Because the amount of lysine in cow's milk is disproportionately low, it is the "limiting amino acid," meaning that it limits how much of the total protein from that food your body can use. According to the WHO, your body requires the ten "essential" amino acids in the following proportion: 11% Isoleucine 22% Leucine 17% Lysine 9% Methionine and Cysteine 14% Phenylalanine and Tyrosine 9% Threonine 2% Tryptophan 15% Valine (Percentages don't add to 100 because of rounding.) Cow's milk contains amino acids in the following proportion: 12% Isoleucine 19% Leucine 10% Lysine 7% Methionine and Cysteine 22% Phenylalanine and Tyrosine 10% Threonine 5% Tryptophan 14% Valine The limiting amino acid of cow's milk is lysine because it makes up only 10% of the essential acids, while your body needs 17%. Cow's milk provides 59% of the lysine your body needs to make full use of the total protein. For comparison, soy protein isolate contains amino acids in the following proportion: 12% Isoleucine 20% Leucine 15% Lysine 6% Methionine and Cysteine 23% Phenylalanine and Tyrosine 9% Threonine 3% Tryptophan 12% Valine For soy protein isolate, the limiting acids are methionine and cysteine. They make up 6% of the essential acids in soy protein isolate, while your body needs 9%. Soy protein isolate provides 73% of the methionine and cysteine your body needs to make full use of the total protein. _ How Much Protein From Dairy and Soy Your Body Can Use _ While other factors affect the use of protein in the body, these limiting amino acids allow your body to use 59% of the protein in cow's milk and 73% of the protein in soy protein isolate.

Question: What whey protein brand does not contain any arginine as an ingredient? I'm looking for a whey protein brand that does not contain any arginine or creatine because I'm only 15 years old and I've heard that its bad for teenagers. Price and link to a site would be helpful.

Answer: arginine is an amino acid so it is naturally in whey protein. Regular foods that you eat will can contain arginine as well as creatine in some meats. You can take in whey protein and not worry about the arginine content. .....

Question: What cat foods can I buy that contain arginine? So, I am taking this nutrition class, and my teacher mentioned that cats require l-arginine in their diets. So here I am aimlessly searching different cat products, and almost none of them contain arginine? Does anyone know of a cat food that contains this (my cat is 5 years old)? He currently like HIlls Science Diet Sensitive Stomach, but it is not listed in the ingredients! What do I do? I don't want him to get hurt from all that NH3 buildup?

Answer: L-arginine is an amino acid and is present in all animal protein sources. Poultry is a particularly good source. He would only get an abnormal increase in ammonia levels if his kidneys weren't functioning well. All animal proteins have plenty of arginine.

Question: How many equivalence points would you expect in a titration curve of arginine? Arginine (C6H14N4O2 ) Would it be 5 or 3?

Answer: 3. If you follow the link, you see that the 3 amine groups in the side chain can only accept 1 proton due to resonance.

Question: If I were to take L-arginine as a weight lifting supplement, would it be better pre or post workout? I have read up on it a bit and I know that NO-Xplode and those type products are derived from the amino acid L-arginine. If you buy L-arginine in pill form, it is much cheaper yet probably not as effective as any of those pre-lift supplements. If anyone has any personal experience taking it as a lifting supplement, would you need to take it pre workout or would it work just as well taking it any time of the day.

Answer: Take it before, it increases blood flow to the muscles and helps you get better "muscle pump" when you work out". I recommend 3000mg 30 minutes before work out.

Question: How much L-arginine should i take, and with what and how often? I am taking 30 grams of L-arginine daily and have been doing so for about 3 weeks now. I've had a week off of L-arginine and I'm starting to use it again this week. Are there any suggestions for better use of this amino acid in order to get the best result?

Answer: what I had was 1000 grams and I took up to 3 a day, I found the str8 L- arginine to be much better then the high dollar ( forgot the name) I took it with protein L glutamine ,creatine and a multi vitamin. and good food .It works wonders

Question: How safe is the supplement argi9? In general is arginine safe to use? Just want to know if it is safe to supplement with arginine? Thanks for your help! This is a great service that yahoo. provides.

Answer: Don't take supplements. Taking one good nutrient puts your body out of whack with other good nutrients...upsets balance. Get all your nutrients from good, organic (especially raw) foods.

Question: Why is arginine essential in infants but not in adults? I'm studying Metabolism Biochemistry and I have that doubt. I know that adults can synthesize arginine by the urea cycle and infants can't. But how biochemically? I understand how the urea cycle occurs. But why can't that happen in infants?

Answer: Pathway is shown in the diagram in link below.

Question: What's the difference between Arginine and L-Arginine? Is L-Arginine just a higher dose or what's the difference? Do they both do the same thing in the body?

Answer: Arginine is an amino acid that is synthesized by the urea cylce in adults, and is an essential nutrient required in babies. The L-form of Arginine is one of the most common 20 amino acids. To understand the L-form, you need to understand chirality. A molecules symmetry at the chemical level determines its chiral nature. Basically, a molecule is chiral if it cannot be superimposed on its mirror image. Chiral moleculaes can be given many different names/forms depending on its configuration. As such, L-Arginine is a optical isomer- whereby the COOH and NH2 groups are arranged in the anti-clockwise manner from the hydrogen (if it was clockwise, it would be in R-form). Like enzymes the structure of amino acids can affect its function, particularly if it is meant to fit in a certain way of the protein. For example, this could affect the spatial measurements of a protein, thus possibly altering the protein function. Hope this helps a little- i have put in the website for chirality on wikipedia to help you out! All the best

Question: How many ATP molecules are produced per arginine phosphate phosphoryloated? How many ATP molecules are produced per arginine phosphate phosphoryloated?

Answer: 3

Question: Has anyone ever used Arginine cream on breast?It is supposed to increase circulation and therefore the. size? I have read on internet that Arginine increases the circulation of breast tissue and makes it more firm and prevent sagging. Any suggestions? has anyone used it ever?

Answer: No creams or pills can increase breast size. Save your money.

Question: Will arginine and ornthine help me get ripped fast? By ripped i mean buff, husky, you know. Will arginine and ornthine combine with intence daily workout help me get big fast? Best answer gets a cookie!

Answer: Your eating is going to determine if you get big or not. Arginine is an energy provider that will clear your mind and give you focus during your workout - but you can get the same effect from a few shots of espresso or a medium coffee 20 minutes before you hit the gym floor. An intense workout will, yes, help your build strength and good muscle tears which are essential to build new muscle - but 80% of "getting big" happens in the kitchen. You need to be eating a ton of protein, and making sure you get enough vitamins and minerals from fresh, healthy foods. If it were up to me I'd dump buying the arginine and spend that money on eating extra chicken breasts for the protein.

Question: A mutation imparting contitutive synthesis of an enzyme of arginine? biosynthesis in Citrobacter was found. The enzyme is normally repressible by arginine. What two kinds of regulatory mutations might cause this phenotype and what kind of mutation in an enzyme of arginine biosynthesis might cause this phenotype?

Answer: One obvious answer is the loss of the allosteric inhibitory site on the enzyme where arginine binds and inhibits the enzyme. This may come from a point mutation but not a nonsense mutation. Another type of mutation may exist where a regulatory subunit is suppose to attach and prevent the activation of the enzyme. A mutation in either the regulatory subunit or catalytic subunit may impair complementarity and prevent the regulatory subunit from binding.