food and nutrition


Ldl

Question: what is the difference between LDL and VLDL? Looked at my mom's cholesterol test results and couldn't figure out the difference between LDL and VLDL. Any information is much appreciated.

Answer: Low-density lipoprotein (LDL) is a class of lipoprotein particles that varies in size (18-25 nm in diameter) and contents (while carrying fatty acid molecules in blood and around the body). It is the final stage of VLDL (very low-density lipoprotein) which is produced by the liver. The LDL contains the apolipoproteins B-100 (Apo B-100, a protein with 4536 amino acid residues) and Apo E.[1] It also contains antioxidative vitamins (vitamin E or carotinoids). It is commonly referred to as bad cholesterol as high LDL levels can lead to cardiovascular disease. Generally, LDL transports cholesterol and triglycerides from the liver and small intestine to cells and tissues which are taking up cholesterol and triglycerides. Very Low Density Lipoprotein (VLDL) is a lipoprotein subclass. It is assembled in the liver from cholesterol and apolipoproteins. It is converted in the bloodstream to low density lipoprotein (LDL). VLDL particles have a diameter of 30-80 nm. VLDL transports endogenous products where chylomicrons transport exogenous (dietary) products. VLDL transports endogenous triglycerides, phospholipids, cholesterol and cholesteryl esters. It functions as the body's internal transport mechanism for lipids.*


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