food and nutrition


Adenosine

Question: What are the differences between adenosine kinase and adenylate kinase proteins in plants? I'm supposed to post a question on bioinformatics for my plant biology class that I will research and answer in the future. I wanted to ask what the structure and purpose or adenosine kinase was in arabidopsis plants, but I also discovered an enzyme called adenylate kinase. If anyone knows the functions/differences between these proteins it would help me to develop a good research question.

Answer: Adenosine kinase (ADK) is involved in the salvage pathways of both adenine (Ade) and Ado and thus is a component of the adenylate metabolic network. Ade and Ado salvage activities are important for a number of reasons: (a) They prevent the accumulation of possibly inhibitory concentrations of these purines; (b) they efficiently recycle Ade and Ado into the adenylate pools; and (c) they convert cytokinin (CK) bases and ribosides to their corresponding nucleotides. Because cytokinin bases and possibly ribosides are thought to be the active forms of cytokinins, their conversion to the inactive nucleotide may be important in regulating the level of this hormone in plant cells. Adenosine monophosphate kinase (AMK; adenylate kinase) catalyses the reversible formation of ADP by the transfer of one phosphate group from ATP to AMP, thus equilibrating adenylates.


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